Sepsis abdominal fisiopatologia pdf filetype pdf

Pneumonia, uti, abdominal pain, diarrhea, meningitis, skinsoft tissue or catheter site inflammation, joint swelling, purulent wound. Sepsis, choque septico, reanimacion en sepsis y embarazo. Abstract sepsis is a syndrome complicating any severe infection, and it is triggered by a variable systemic host response, leading to generalized tissue damage. The 2001 sccmesicmaccpatssis international sepsis definitions conference. Each year, sepsis affects up to 3 million people in the united states. The term sepsis encompasses a spectrum of disease ranging from systemic inflammatory response syndrome sirs to severe sepsis and multiple organ failure. Intrabdominal sepsis is a frequent clinical disorder in inpatients with severe consequences as septic shock and multisystem organic fallure. Abdominal sepsis represents the hosts systemic inflammatory response to bacterial peritonitis.

Epidemiological, pathophysiological and clinical fundamentals of sepsis in children. Peritonitis y sepsis abdominal gastroenterologia accessmedicina. As part of the bodys inflammatory response to fight infection, chemicals are released into the bloodstream. These chemicals can cause blood vessels to leak and clot, meaning organs like the kidneys, lung, and heart will not get enough oxygen. Fluids and antibiotics must be given as quickly as possible. Numerous conditions can be sources of infection in patients who have sepsis. Sepsis does not have a characteristic clinical picture, and its diagnosis is based in a high suspect index and the verification. Even with intensive care, rates of inhospital death from septic shock were often in excess of 80%. Sepsis continues to be a primary cause of high mortality and morbidity in critically ill patients. In an era of increasing antimicrobial resistance, selecting the appropriate regimen is important and, with new drugs coming to the market, correct use is important more than ever before and abdominal infections are an excellent target for antimicrobial stewardship programs. Despite constant growth in dedicated basic investigation and numerous clinical studies, no remarkable developments have been made for effective and innovative therapies. Abdominal infections are an important challenge for the intensive care physician.